A group of researchers at the Korea Advanced Institute of Science and Technology (KAIST) has modified an anti-aging enzyme in roundworms, which opens the door to the possibility of designing drugs to combat age-related diseases and allow humans to live longer. According to the British newspaper “Daily Mail”, the Korean researchers were able to connect the age of the creatures up and down, by changing the levels of protein activity, as the modified enzyme allows roundworms to convert sugar into energy, when cellular energy decreases, which the team found a way to control on him.
The researchers said that humans possess these proteins, which provides the possibility of developing drugs that enhance longevity, noting that they were able to enhance the lifespan of worms, by interfering with some of the proteins involved in monitoring the energy use of their cells. The proteins “VRK-1” and “AMPK” work side by side in roundworm cells.
The first tells the latter to work by attaching a phosphate molecule made up of one phosphorous and four oxygen atoms to it. The latter’s role is to monitor energy levels in cells, when cellular energy decreases. Using a range of different biological research tools, including the insertion of foreign genes into the worm, the researchers were able to request the activity of the gene, which requires cells to produce the protein “VRK-1